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Clinical trials showed that the medications were both safe and effective and helped people lose significant percentages of their body weight
IL-22 mainly activates the Jakl/Tyk2-STAT3 pathway by binding to the IL-22R1 and IL-10R2 heterodimer receptors, thereby exerting effects such as hepatocyte survival, liver regeneration, and reducing inflammation and oxidative stress (Xiang et al., 2020a)
Heerspink, J.F.E
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