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However, with increasing doses of acetaminophen, there is progressive dislocation of nuclear translocation, transcription, translation and protein activity as the rate of drug bioactivation over-whelms cell defence through the destruction of crit-ical proteins at least 31 of these critical proteins have been identified (Park et al ., 2005)
CONTRIBUTING EXPERT Chandar Abboy, MD Dr
It may increase pain thresholds, though effects are milder and shorter-lived than opioids
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