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Hohe Konzentrationen finden sich in der Leber, Lunge, Niere, den Schleimhuten des Magen-Darm-Trakts und im Gehirn
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In this review, we will focus on the metabolic effects of IGF-1, the concept of metabolic syndrome and its clinical manifestations (impaired lipid profile, insulin resistance, increased glucose levels, obesity, and cardiovascular disease), discussing whether IGF-1 replacement therapy could be a beneficial strategy for these patients
Peptide therapy, at its most rigorous, attempts to restore specific signaling functions that have degraded with time
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