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In a 2003 cell-culture study published in Bulletin of Experimental Biology and Medicine , Khavinson and colleagues reported that Epithalon induced telomerase activity and produced telomere elongation in telomerase-negative human fetal fibroblast cultures, with the authors concluding that the peptide may extend the proliferative lifespan of cell populations through anti-senescence activity [1]

Furthermore, our work confirmed previous observations that the reductive metabolism of TNBS by specific flavoproteins, eg, GSSG reductase, generates ROS, including hydrogen peroxide (Grisham et al, 1991)

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