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Its short sequence Gly-His-Lys binds Cu2+ ions with exceptional affinity through the histidine imidazole ring and the terminal amine, forming the characteristic blue complex
What makes cagrilintide particularly interesting from a pharmacological standpoint is that it appears to produce a preferential loss of fat mass rather than lean mass a finding observed in preclinical and clinical studies
Jose et al
Pharmaceuticals (Basel)
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