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En modelos animales preclnicos, dado su carcter de molcula pequea oral-activa, los diseos han contemplado dosificacin por va oral o intraperitoneal segn el protocolo aprobado por el comit de tica institucional, con esquemas de administracin diaria y ventanas de tratamiento que abarcan varias semanas para observar efectos sobre composicin corporal
Injections are easy to do
Glucose sensing and signalling
However, long-term safety in humans has not been established , and risks may increase with improper sourcing, excessive dosing, or chronic use
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