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We assessed cytochrome P450 3A4 (CYP3A4) activity in the derived smHLCs (under all conditions), by analysing the ability of the cells to induce CYP3A4 upon challenge with the proto-typical inducer Rifampicin
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PMID: 31446075
This period typically corresponds with mid range dosing, where appetite suppression is strong but side effects remain minimal with proper medical oversight
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