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Health and lifestyle information included smoking status (non-smoker vs current smoker), alcohol consumption as units per week, physical activity assessed using the International Physical Activity Questionnaire (IPAQ, expressed in Metabolic Equivalent Total (MET) minutes per week [46], and body mass index (BMI) measured during physical examination
In the present analysis, 5 rodent studies reported the IL-1 titres in serum and/or tissue and the mean total of a subgroup of the diabetic group with 20 animals was 57.42 pg/ml and the matching mean total in the healthy control was 34.115 pg/ml, which indicates an increase of 68.31% between the two treatment groups ( Supplementary Figure S1-27
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