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In laboratory and pre-clinical research settings, glutathione is studied across virtually every area of cellular biology owing to its central, non-redundant role in redox homeostasis and its interactions with dozens of enzyme systems, signalling pathways, and disease-relevant biological processes
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Beside its fundamental function in SA biosynthesis, GNE was suggested to regulate sialyltransferase mRNA levels, affecting cell proliferation 8
Primary mouse embryonic fibroblasts were isolated and cultured as described (Scheuner et al., 2001)
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