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Clinical safety and efficacy in humans have not been established
Either people really have to accept this as a treatment for life,, or we in science need to think really, really hard, how to support people when they stop the drug. While the study did not show causality, Jebb speculated that the difference in how fast people put weight back on could be due to the fact that diets are hard and people have to practise restraint to lose weight, whereas if you are taking a drug that knocks your hunger out completely, you dont have to make that effort
Research consistently shows that increasing protein intake to 1.2-1.6g per kilogram of body weight enhances weight loss outcomes regardless of the primary intervention
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