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Well-designed randomized clinical studies are needed to systematically evaluate the evidence for the use of these hepatoprotective agents as treatment options for APAP-induced liver injury, to determine the timing of initiation of the therapy, and to further define the optimal treatment regimen
Safety and efficacy of OZEMPIC have not been established in pediatric patients (younger than 18 years)
Genetic variants within genes encoding protein targets can modulate the expression or functionality of these targets, mimicking the mechanisms of drug actions [28]
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