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Two trials in acutely hospitalized patients have shown that short-term (around 7 days) vitamin C supplementation increased concentrations of ascorbic acid in plasma and leukocytes and led to 34-35% improvements in mood state, as measured by POMS (142, 143)
Result timelines vary by goal
Although it is compatible with hydrating and brightening ingredients, but not with strong exfoliants
They demonstrate great biocompatibility, and both their size and shape can be easily modified to alter their biodistribution [283, 284]
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