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The finding that a long-acting GIP receptor agonist (LAGIPRA) increases insulin sensitivity by promoting glucose capture in WAT confirms this
Unlike small-molecule drugs that often have broad, systemic effects, peptides are large enough to target specific biological pathways yet small enough to penetrate tissues and reach injured areas effectively
concluded that the most effective targets of action were PPARA, SHBG, AKR1B1, PPARG, IGF1R, MMP9, AKT1, and INSR structural domains after network pharmacology intersecting the drug targets of RES with disease targets
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