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Blocking xcactivity with a small molecule inhibitor, SSZ,32 or by knockdown of the xc light chain component xCT, prevented thiol release and significantly reduced MSC protection to levels close to those observed in cells without MSC support
The classes of antifungal compounds responsible for inhibiting -1,3-glucan synthesis and assembly are acidic terpenoids [enfumafungins], glycolipids [papulacandins] and cyclic lipopeptides [echinocandins]
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