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In 3T3-L1 adipocyte cultures, 5-Amino-1MQ treatment reduced adipocyte size by approximately 40%, decreased expression of lipogenic genes DGAT1 and DGAT2 (diacylglycerol acyltransferases responsible for triglyceride synthesis), and reduced total lipid accumulation
In the article the collaborators argued that GLP-1 (1-37) 'may be prohormone or precursor for the GLP-1 (7-37) peptide that is processed from GLP-1 (1-37) by the cleavage at the single arginine residue at position 6' (Mojsov, Heinrich, Wilson)
In this pathway, homocysteine is converted into cystathionine and then cysteine, which is a direct precursor for glutathione synthesis
(12) Gardenia Scientific name Gardenia jasminoides
