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Understanding the unique risks and opportunities of GLP-1 use during perimenopause could unlock tremendous improvements in treatment success, reduce costly discontinuation and weight cycling, and prevent serious psychological and physical harm.
In addition to its glucoregulatory effects, GLP-1 was shown to interact with other organs as well, which is not surprising given the widespread expression of GLP-1 receptors in the human body
Since these drugs have only been widely prescribed for a few years, longer term follow-up will be important
However, the funders had no role in the study design, data collection and analysis, publication decision, or manuscript preparation
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