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In the Phase 2 trial protocol, participants began at a low starting dose commonly 2 mg once weekly before progressing through incremental increases over several months, with target maintenance doses ranging from 8 mg to 12 mg weekly depending on tolerability and clinical response
That said, being a few hours early or late generally isnt going to hinder your progress
Cumulative incidence estimates are based on time from randomization to first EAC-confirmed MACE with non-CV death modeled as competing risk using the Aalen-Johansen estimator
Check your refrigerator temperature and ensure the vial is not near the freezer compartment or exposed to temperature fluctuations
