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Neuroendocrinology Letters, 24 (3/4), 233-240
Steady glutathione levels sustain the brightening effect, which is why skipping treatments tends to slow visible progress
In this review, we focus on the mechanistic role of the UPS in circadian clock regulation, summarize key E3 ligases and deubiquitinating enzymes implicated in clock protein turnover, and highlight the essential role of the UPS on sleep timing and overall circadian biological homeostasis
Usman MW, Gao J, Zheng T, et al
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