Acetylcholinesterase Active Site Mighty Model© ACHE Active Site Mighty Model Set:ACHE Active Site Mighty Model group discussion

group discussion

Discover the semiconservative nature of DNA replication

and biochemistry

The crucial role of iron in the heme group

Acetylcholinesterase Active Site Mighty Model© ACHE Active Site Mighty Model Set:ACHE Active Site Mighty Model group discussionMany common insecticides work by targeting the enzyme acetylcholinesterase. This fold out model makes the enzymes crowded active site more approachable, as it lets students experiment with a magnet docked substrate (acetylcholine), inhibitor (insecticide), and mutant side chain (serine). Students can immediately intuit how one mutation, Gly119Ser, blocks the insecticide from fitting in the active site. Through modeling, your students will learn: The