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FIGURE 4 3.5 FOXO4-DRI inhibits FOXO4-P53 binding and promotes P53 phosphorylation To further elucidate the specific mechanism of FOXO4-DRI in anti-aging, we induced senescence in endothelial cells under OGD conditions and treated these cells either PBS or FOXO4-DRI
They did not indicate that the two medications are contraindicated or unable to be taken together
AKT signaling also influences glucose metabolism by regulating GSK-3 activity and protein synthesis and cell growth by regulating the activity of the mTORC1 complex (Welsh et al., 1998)
Chen L, Ding Y, Cagniard B, Van Laar AD, Mortimer A, Chi W, et al
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