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Functional and phenotypic analyses confirm the induction of a pancreatic endocrine fate, including positive dithizone (DTZ) staining indicative of insulin production, as well as the upregulation of key pancreatic markers such as Nestin , PDX-1 , paired box gene 4 ( PAX4 ), neurogenin 3 ( NGN3 ), Isl-1, MAFA, insulin, and glucose transporter 2 ( GLUT2 )
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This study was recently published in the journal Previous research has shown GLP-1 may play a role in Additionally, GLP-1 mRNA expression has been noted in certain types of immune cells, such as A process called costimulation a secondary signal that immune cells need to activate an immune response is vital for T lymphocytes to work correctly
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