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Anyone on anticoagulant or antiplatelet therapy given effects on blood vessel formation and healing, caution and medical oversight are warranted

Ongoing studies continue to expand our understanding of its role in antioxidant defense, mitochondrial physiology, detoxification pathways, immune regulation, and cellular resilience under conditions of physiological stress

Avoid injecting directly over the patella, where there is minimal subcutaneous fat over bone

Verify the current MAC LCD for the most recent coverage determination before billing semaglutide or tirzepatide for non-diabetes indications Source: CMS LCD Database RCM teams managing injection billing must verify that their billing software reflects the April 2026 quarterly MPFSDB update