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Mitochondria are major sources of free radicals, and in addition to being commonly used to treat disoriented circadian clocks due to jet lag and other disturbances (i.e., sleep inefficiency) 18 , melatonin has been widely used as an antioxidative therapy 19 and its use dates back to 1993 (refs

3) Helps Insulin Sensitivity People with type-2 diabetes and impaired glucose tolerance may have lower circulating levels of glutathione and decreased glutathione metabolism

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