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Mood changes such as irritability, depression, or anxiety, as well as numbness or tingling in the hands and feet, can also be linked to low B12 levels
1 Asymptomatic autoimmune gastritis likely precedes gastric atrophy by 10 to 20 years, followed by the onset of iron-deficiency anemia that occurs as early as 20 years before vitamin B 12 deficiency pernicious anemia
PMCID: PMC10641821
For FOXO4-DRI, literature has examined senescent fibroblast, Leydig-cell, chondrocyte, and endothelial-cell model contexts [3], [10], [11], [19]
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