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Gastrointestinal adverse effectsparticularly nausea, vomiting, and diarrhoeaare common during the initial weeks of Mounjaro therapy

GLP-1-induced weight loss directly translates to reduced joint stress, slowing cartilage degradation and improving mobility

Urinary Tract Infection (UTI): Frequent urination accompanied by dysuria (painful urination), urgency, suprapubic discomfort, or cloudy/malodorous urine suggests possible UTI

For patients with Long COVID or ME/CFS, practitioners often recommend starting with a smaller dose (e.g., 1/4 or 1/2 scoop) to assess tolerance, as rapid detoxification can sometimes cause a temporary exacerbation of symptoms (a Herxheimer reaction) as toxins are mobilized