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The study points to several anti-inflammatory effects that matter in MCAS: * Reduced activation of inflammatory pathways like TNF- and NF-B * Suppression of the NLRP3 inflammasome (a key driver of chronic inflammation) * Calming of mast-cell-driven immune overactivity In simpler terms: these medications may help mast cells chill out
Tahrani, A
Elsevier, pp 409439 Raghu G et al (2021) The multifaceted therapeutic role of N-acetylcysteine (NAC) in disorders characterized by oxidative stress
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