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Macrophage-associated lipin-1 promotes -oxidation in response to proresolving stimuli

For example, a dysbiotic microbiota can promote ferroptosis by suppressing SLC7A11 expression, which limits cysteine uptake and GSH synthesis, while concurrently enhancing acyl-CoA synthetase long-chain family member 4 (ACSL4)-driven lipid peroxidation (41)

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The effects of each patient covariate (i.e., gender, age and L-carnitine treatment) on the toxicokinetic parameters were systematically tested