Cryo-EM methods Negative staining transmission electron microscopy The homogeneity of the protein before structural determination was assessed by negative staining electron microscopy
12 The matched factors included demographics (age at index event, sex, race, and ethnicity), diagnoses (chronic kidney disease, obstructive sleep apnea, and nicotine dependence), medications (amiodarone, dipeptidyl peptidase 4 (DPP-4) inhibitors, insulin and insulin analogs, sulfonylureas, biguanides, sodium-glucose co-transporter 2 (SGLT2) inhibitors, and thiazolidinediones), and clinical laboratory values like body mass index and hemoglobin A1c levels
Torrioli MG, Vernacotola S, Mariotti P, et al
Tirzepatide may produce greater weight loss (20-22% vs