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Research demonstrates that co-administration produces amplified GH pulses exceeding the sum of individual peptide effects, suggesting receptor-level synergism between GHRH and ghrelin pathway activation

5-HTT / rats (Slc6a41Hubr) were generated on a Wistar background by N -ethyl- N -nitrosurea (ENU)-induced mutagenesis ( +/ rats that were outcrossed for at least 12 generations with wild-type Wistar rats obtained from Harlan Laboratories (Horst, The Netherlands)

Schafe FQ, Buettner GR (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple