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The glutathione peroxidase, which is responsible for protecting lipids and proteins from oxidation, is regulated by the essential trace metal element Selenium (Se) [124]
Interestingly, the reduction in HbA1c was already evident after the first 4 weeks of treatment and remained statistically significant up to the end of the 52-week observation period, supporting the evidence of rapid efficacy of the drug and great durability, which was independent from weight loss
Diabetes Metab Res Rev (2010) 26(4):28796
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