If you're increasing fiber to help with acid reflux, do it slowly over several days
Nicholls reports receiving grant/research support from Amgen, Anthera, AstraZeneca, Cerenis, Cyclarity, Eli Lilly, Esperion, InfraReDx, LipoScience, NewAmsterdam Pharma, Novartis, Resverlogix, Roche, Sanofi-Regeneron and The Medicines Company, and consulting for Abcentra, Akcea, Amarin, Anthera, AstraZeneca, Boehringer Ingelheim, CSL Behring, CSL Seqirus, Daiichi-Sankyo, Eli Lilly, Esperion, Merck, Omthera, Resverlogix, Sanofi-Regeneron, Scribe Therapeutics, Silence Therapeutics, Takeda and Vaxxinity
This means there is no established pharmacological mechanism by which semaglutide would be expected to cause spotting or bleeding between periods
Aversion to fatty or rich foods is another observation