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However, the peptide's mechanism offers a theoretical basis for cycling: sustained nightly stimulation of the same neuroendocrine cascade could lead to receptor downregulation or diminished signaling over time
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Renal impairment affects not only the renal excretion of a drug but may also alter metabolism and active transport in the kidney, liver or gut and affect absorption, tissue distribution and plasma protein binding [13]
She has now had minimal to no symptoms for several months, and is completely off her Elmiron
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