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Janelidze S, Hertze J, Ngga K, Nilsson K, Swedish BioFINDER Study Group, Nilsson C, Wennstrm M, van Westen D, Blennow K, Zetterberg H, Hansson O (2017) Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype
Mining of the proteome data for GSH-associated genes showed that disruption of the pathway for the synthesis and degradation of glutathione in the Atggt1 (-glutamyl transpeptidase, which has a function in the degradation of GSH S-conjugates in the vacuole) knockout leaves was associated with the induction of genes encoding four GSTs in the phi class (AtGSTF2, AtGSTF6, AtGSTF9, and AtGSTF10 Ashraf et al., 2010)
It analyzes pathway-level variants (GIPR and FTO) that relate to the biology involved, offering context for a conversation with your provider rather than a prediction
For women with PCOS or insulin resistance, GLP-1s may help restore ovulation
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