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2021;16(2):e0245052

The behavioral effects on eating are well-documented in clinical literature: Dramatically reduced portion sizes: Clinical trials show semaglutide users lose an average of 1315% of body weight and tirzepatide users 1722%, driven largely by significant reductions in portion size and overall food intake

Although the study did not show significance on the primary objective of change in coronary luminal diameter as assessed by quantitative coronary angiography, the data suggested a favorable outcome with respect to fewer hospitalizations for angina and revascularization procedures in patients with CAD