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In brown adipose tissue, the Sel1L-HRD1 complex is essential for maintaining mitochondrial integrity and thermogenic capacity
This corresponded to a 0.34 mmHg reduction in systolic blood pressure for every 1% of weight loss
Interested in science from a young age, most of Bloom's career has been focused on gut hormones
Activation of STING triggers a signaling cascade involving TBK1, IRF3, and NF-B, leading to the production of pro-inflammatory cytokines and further endothelial damage
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