This is based on our observations in the Cart igf-1r conditional knockouts, where we found decreased type II collagen and Ihh expression, but increased expression of PTHrP, potentially explaining the growth plate defects in these animals (Wang et al., 2011)
Weight loss, once a clinical outcome, has become a visible marker of personal virtue, performative achievement, and conformity to dominant beauty and health ideals, reflecting broader neoliberal healthism ideals that conflate appearance with moral responsibility
Most plans want documentation of prior weight loss attempts (diet apps, coaching, nutrition programs, etc.) and comorbidities Know what documentation details: For CVD prevention (Wegovy): Document prior MI, stroke, PAD, or revascularization
After this date, only products that are FDA-approved or have been through the FDA process and are proven safe and effective in large populations and prescribed by a medical professional should be on the market