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TGA scheduling decisions
[Our] basic thinking on AOD9604 is that the drug failed because it was made orally available, which likely reduced bioavailability and also potentially resulted in protein denaturisation in the gastrointestinal tract, which would have reduced the drugs activity
This is mechanistically novel for the GLP-1 class
These studies focus strictly on molecular resilience and signaling integration within controlled research environments, rather than any physiological recovery or therapeutic outcomes
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