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Sexual function is tightly coupled to adiposity through at least four pathways: androgen metabolism, hypothalamic-pituitary-gonadal (HPG) axis suppression, endothelial function, and inflammatory burden
doi: 10.1172/JCI196346
*Correspondence: Xian-Feng Zhang, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Obesity, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Obvious neurological and/or cardiovascular symptoms may represent a culmination of gastrointestinal beriberi, probably triggered by challenges that increase metabolic demands or decrease intracellular transport of thiamin, such as stress, infection, trauma, drug administration
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