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Claims regarding GLP-1 support are not backed by solid human research
Vagal innervation of the hepatic portal vein and liver is not necessary for Roux-en-Y gastric bypass surgery-induced hypophagia, weight loss, and hypermetabolism
This finding has been corroborated across different preclinical models, where impaired BCAA catabolic activities and increased BCAA levels were observed in the several preclinical HFpEF models 93,94
Moreover, OCTN2 mediates the tissue distribution of carnitine, ensuring that these tissues receive sufficient carnitine to maintain their normal functions [164]
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