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In rare cases, GLP-1 receptor agonists can lead to more serious side effects, such as pancreatitis (inflammation of the pancreas), thyroid tumours, or kidney problems
However, for those on GLP-1 agonists, studies recommended increasing protein consumption to 1.2-2.0 grams per kilogram of body weight
In patients with severe hepatic impairment (Child-Pugh=10-15) or hepatic cirrhosis, it may be necessary to reduce the dose by 50% or more [see Use In Specific Populations ]
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