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A meta-analysis of 22 randomized controlled trials highlighted that patients with AD who received more than 12 weeks of melatonin treatment showed improvements in Mini-Mental State Examination scores, particularly in those with mild AD [219]
For those without absorption issues, high-dose oral B12 is generally comparable in raising levels
It increases your overall antioxidant defense, a task that can never be accomplished just with one substance [1]
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