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Goldstein, L
Clinical data support this, with Hinge Health reporting a 15% increase in muscle mass retention when combining Ozempic with regular exercise, indicating that pairing resistance training with semaglutide helps retain more lean tissue during active weight loss
Theres also evidence that GLP-1s affect reward pathways in the brain
In a phase 1, randomized, double-blind, placebo-controlled clinical study in participants with obesity (NCT04478708), AMG 133 had an acceptable safety and tolerability profile along with pronounced dose-dependent weight loss
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