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ACTIVATED CHARCOAL: A Universal Antidote Ultrafine, activated charcoal contains millions of tiny pores that capture and remove positively charged toxins in the gastrointestinal tract, and thus charcoal has long been considered a universal antidote in acute and chronic poisoning.32,33,34 Charcoal is effective at removing metals35, bacterial endotoxins36, plant toxins and alkaloids, pharmaceuticals37, and gasses and vapors38, among other substances