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doi:10.1002/jac5.1999 Lowe D
Currently, platinum-based chemotherapy in OC treatment increases intracellular ROS levels, leading to damage to macromolecules such as nucleic acids and proteins, ultimately resulting in cell death
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[1] Licensed pharmacological options in the UK include orlistat (available at BMI 30 kg/m, or 28 kg/m with weight-related risk factors) and semaglutide (available within specialist weight management services as per NICE TA875, with adjusted BMI thresholds for some ethnic groups)
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