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With sufficient glutathione present, NAPQI is very quickly metabolized into sulfate and cysteine compounds, which are readily excreted through the kidneys.[ref] However, when it isnt neutralized, NAPQI is highly reactive and can cause oxidative stress and damage to the liver cells, hepatocytes, leading to cell death
This reduces blood sugar levels and decreases the amount of glucose available for conversion to fat
The aortic endothelium was then placed in a medium containing 1 M DHE and incubated at 37 C for 1 h
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