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Conclusion Whilst severe B12 deficiency has a clear clinical picture with characteristic haematological and/or neurological features, establishing mild or borderline deficiency can be problematic as serum levels are maintained at the expense of tissue concentrations, and therefore serum levels of B12 may be in the low normal or borderline range despite a deficiency

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SLU-PP-332 SLU-PP-332 is a synthetic small-molecule ERR (estrogen-related receptor) pan-agonist under investigation for its role in mitochondrial biogenesis, skeletal muscle fiber-type switching, and metabolic regulation

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