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To determine if pharmacological manipulation of autophagy effects SIPS, we treated GSH-depleted cells with the autophagic inducer rapamycin and autophagic inhibitors 3-MA and Baf-A1
6 Larger clinical trials are warranted to further elucidate these findings
Glutathione and cold sores Cold sores are primarily caused by HSV-1, a virus that induces oxidative stress upon infection and generates ROS, which can damage cellular components and exacerbate the inflammatory response
PMID 18885611
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