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Some people develop deficiencies due to dietary patterns, others due to absorption challenges in the gut, and some simply because chronic stress and inflammation increase nutrient demand
Understanding real transformation timelines helps calibrate expectations
Patients on this protocol who also use metabolic support agents like Metformin should note that both agents activate AMPK, and physician oversight is warranted to avoid compounding effects on blood glucose that could theoretically cause hypoglycemia in susceptible individuals, though this has not been reported clinically with MOTS-c at standard doses
Since vitamin D facilitates calcium absorption, there is a tendency that it will cause gastrointestinal distress and lead to a buildup of calcium
