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Oral administration of allicin to mice lowered ROS production and prevented ROS-induced cardiac hypertrophy by inhibiting pro-inflammatory pathways like mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/glycogen synthase kinase 3 (GSK3) signaling pathways (20)
Cancer 12 (12), 860875
Park JM, Lee DH, Kim DH
In an effort to develop such a drug members of our laboratory synthesized a number of AngIV-based compounds possessing extended half-lives by utilizing reduced peptide bonds (CH2-NH2) between residues
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