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On the gastrointestinal front, literature has described mucosal barrier protection via modulation of endogenous prostaglandin (PGE2) and heat shock proteins (HSP70/90)
These elements contribute to maintaining a balanced diet by supplying essential vitamins and minerals that support physiological processes
A 2024 npj Aging paper (doi:10.1038/s41514-024-00160-6) demonstrated that adiponectin receptor expression on B cells declines with age, reducing endogenous PEPITEM levels and allowing progressive T-cell infiltration of metabolically active tissues a direct molecular mechanism for inflammaging
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